Efficacy of pectoral nerve block versus intercostal nerve block for postoperative analgesia after breast cancer sur-gery
LIU Tian-xiao
LI Yan-hua
CHEN Jing
XIE Yu-bo
Abstract：Objective To compare the efficacy and safety of ultrasound -guided pectoral nerve ( Pecs) block with intercostal nerve block for perioperative analgesia for breast cancer surgery .Methods Ninety patients undergoing breast cancer surgery were randomized with random number into 3 groups.Patients in Group P received ultrasound -guided pectoral nerve block combined with general anesthesia .Patients in Group I received ultrasound -guided intercostal nerve block combined with general anesthesia .Patients in Group G received general anesthesia alone .Same induction of general anesthesia was applied in all the three groups .Postoperative pain was assessed using a numerical rating scale (NRS).The vital signs and pain score were recorded 3 h, 6 h, 12 h, 1 d, 2 d and 3 d after surgery.The incidences of postoperative nausea and vomiting (PONV) was recorded 3 h, 6 h, 12 h, 1 d, 2 d and 3 d after surgery.The total propo-fol and remifentanil amounts of perioperative were recorded .The operating time of pectoral nerve block and intercostal nerve block were recorded .All block-related complications , such as hypotension , vascular puncture, or pneumothorax, were recorded.The duration of surgery and anesthesia were recorded .Results Compared with Group G, the total con-sumption of propofol and remifentanilamount significantly less than those in Group P and I , with significantly lower NRS scores 3 h, 6 h, 12 h, 1 d, 2 d and 3 d after surgery (P＜0.05).Compared with Group G, the incidences of PONV 3 h, 6 h and 12 h after surgery were significantly lower in group P and group I ( P＜0.05).The operating time of nerve block was significantly less in Group P than that in Group I (P＜0.05).There was no significant difference in the con-sumption of propofol and remifentanil , the NRS score and the incidence of PONV between Group P and I (P＞0.05).No block-related complication was reported in both two nerve block groups .Conclusion Both ultrasound-guided pectoral nerve block and intercostal nerve block are safe in breast cancer surgery can reduce the usage of propofol and remifentanil , postoperative NRS score, and the incidence of PONV, without causing any adverse effect .The pectoral nerve block is sim- pler and easier applied in clinic.
Keywords：pectoral nerve blockintercostal nerve blockpostoperative painbreast cancer surgery
Publication Date：2018-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 1501-1504,1508 )