The expression and significance of Neun antigen in neurofibroma and neurilemmoma
YANG Xi-tong
FAN Xiang
LI Zheng-jin
ZHAO Li-xian
WANG Guang-ming
Abstract：Objective To investigate the expression and significance of Neun antigen in neurofibroma and neurilemmoma. Methods The tissues from 74 cases of nerve tumors, which includes 3 cases of autopsy, 5 cases of leiomyoma, 5 cases of solitary fibrous tumor, 5 cases of fibrocellular tumor, 5 cases of gastrointestinal stromal tumor, 27 cases of neurofibroma, and 24 cases of neurilemmoma were collected. All the samples were stained with anti-Neun monoclonal antibody through immunofluorescence. Results All the cases of leiomyoma, Solitary fibrous tumor, fibrocellular tumor and gastrointestinal stromal tumor was Neun negative. The Neun-positive ratio was 92. 59％ ( 25 /27) in neurofibroma and 70. 83％ ( 17 /24) in neurilemmoma. Conclusion The anti-Neun monoclonal antibody is used to assist the diagnosis of the neurofibroma and neurilemmoma.
Keywords：Neuron-specific nuclear proteinneurofibromaneurilemmoma
Publication Date：2018-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 364-367 )