Effects of dietary fiber on common risk factors for cerebral infarction patients and high -risk population in Guangzhou communities

ZHAO Qiu-ge; FANG Xiao-tao; YE Feng-yi; WU Jia-qian; ZENG Zi-qi; YE Chen; SHEN Yue-chun; TIAN Zuo-jun

doi:10.3969/j.issn.1001-9448.2018.02.013

Abstract：Objective To investigate the effects of dietary fiber(DF)on the common risk factors of patients with cerebral infarction and high -risk population in Guangzhou communities.Methods Totally 180 interviewees with cere-bral infarction and high -risk population were collected from Guangzhou communities.The DF intake was estimated ac-cording to the"dietary fiber food frequency questionnaire"and the"Chinese food composition".The data was divided into three groups based on the cut -off points with DF of 10 g and 25 g.The univariate and multivariate analyses were carried out for assessment of clinical risk factors.Then the data was split into hypertension and non -hypertension subgroups,and further into group of DF≥20 g and group of DF <20 g within the two subgroups, respectively.The clinical parameters were compared between DF≥20 g and DF<20 g groups.Results the Crouse score of carotid plaques of patients with DF<10g was significantly higher than that of patients with DF 10-25g(P=0.037),and higher compared with patients of DF>25 g though there was no significant difference revealed(P=0.06).Ordinal regression showed that only Crouse score showed statistical significance among the three DF groups(Wald=4.459,P=0.035).Additionally,DF was sig-nificantly negatively correlated with Crouse score(r=-0.183,P=0.014).In the hypertension subgroups,total choles-terol and low density lipoprotein were significantly higher in hypertension patients with DF <20 g than those in hyperten-sion patients with DF>20 g(t=2.500,P=0.014;t=2.458,P=0.015).Conclusion The decrease of DF intake is not onlyan independent risk factor for carotid plaque formation in cerebral infarction patients and high -risk population in Guangzhou communities,but also a risk factor for high blood lipids in hypertensive patients in this region.