Anti-angiogenesis therapy for refractory malignant meningiomas, report of 3 cases and clinical analysis
LI Juan
LAI Ming-yao
ZHOU Jiang-fen
SHAN Chang-guo
HONG Wei-ping
CAI Lin-bo
Abstract：Objective To investigate the effect of anti -angiogenesis therapy for refractory malignant meningio-ma.Methods The clinical data of 3 cases of refractory malignant meningioma treated with anti -angiogenic drug Bev-acizumab (avastin) were retrospectively analyzed .Results Post treatment, the volume of edema was decreased in MR T2 FLAIR images.Two patients had stable enhanced lesion and one patient had increased enhanced lesion .The clinical symptoms of 3 patients were improved , and the progression-free time were 2.5, 5 and 7 months respectively .Conclu-sion Patients with refractory malignant meningioma could slightly benefit from the aid of Bevacizumab post conventional treatment.It is still difficult to cure refractory malignant meningiomas .
Keywords：recurrentrefractorymalignant meningiomaanti-angiogenesisprognosis
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：6( 3748-3753 )