Analysis of the pathology and outcomes of recurrent meningioma
RAO Ying-hua
KE Chao
LI De-pei
ZHANG Ji
WANG Jian
LIN Fu-hua
JIANG Xiao-bing
CHEN Zheng-he
CHEN Yin-sheng
ZHANG Xiang-heng
SAI Ke
MU Yong-gao
CHEN Zhong-ping
Abstract：Objective To determine the result of clinical -pathological features of recurrent meningiomas . Methods All the recurrent meningiomas treated in Sun Yat -Sun University Cancer Center from December 2000 to De-cember 2015 were retrospectively analyzed .Results A total of 57 patients (male, n=29) were confirmed recurrence at the last follow-up, with the mean age of 48.9 years.Thirty-four of them were primary WHO grade Ⅰ, but upgraded at recurrence in 12 patients.Similarly, 4 of 13 WHO grade Ⅱpatients deteriorated at recurrence .In multivariate analysis, WHO grade, Ki-67 index and adjuvant radiation therapy were significantly associated with patient prognosis .Conclusion The WHO grade might increase at the recurrence of meningioma .Patients should be followed regularly , and individual treatments should be suggested based on clinical -pathological features of the tumors .
Keywords：recurrent meningiomahistopathologyprognosis
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 3744-3747 )