A study of preoperative MRI scan sequences for stereotactic visualization of subthalamic nucleus in deep-brain stimulation procedures for patients with Parkinson′s disease
LUO Xiao
HE Pin
CAI Xiao-dong
ZHANG Dou-dou
WU Qing-pin
YAO Wei-wei
LEI Yi
XIA Jun
Abstract：Objective To investigate and comparative the best MRI sequences to visualize the subthalamic nucle-us ( STN) as the operation target .Methods Ten patients with PD were included .Ten healthy subjects were taken as control group .Sequences that we chose were compared with the conventional sequences .Different sequences were ana-lyzed semi-quantitatively when applied to visualize the STN before DBS procedures .The intra-operative microelectrode recording ( MER) electrode probe positioning was reviewed and confirmed after operation .Results The T2 flash 2D, T2-SPACE and SWI sequences were higher than conventional T 1-mprage, T2-TSE and FLAIR in semi-quantitative scores, with higher consistency with the intra -operative MER confirmed electrode probe positioning .Conclusion T2 flash 2D, T2-SPACE and SWI sequences can provide accurate targeting for STN deep brain stimulation , and can improve the positioning accuracy , avoid complications and improve the operation efficiency .
Keywords：subthalamic nucleus deep brain stimulationParkinson′s diseaseMagnetic resonance imaging
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 2946-2949 )