Association between type 2 diabetes mellitus and lung function decline in Southern Chinese
CHEN Xiao -li-ang
CHENG Jin-quan
CHEN Chang-chang
CHEN Jian-dong
ZHAI Yu-han
YU Yan
LIN Jin-bo
JI Jia-jia
Abstract：Objective To explore the association of type 2 diabetes mellitus with lung function decline and COPD and provide evidence for comprehensive intervention of type 2 diabetes. Methods 1:1 matched case control study was applied to enroll the subjects,as the lung function and risk factors were investigated by the spirometer and self-made questionnaire in cases and controls. Results 216 pairs of cases and controls were recruited in this study. The means of FVC,FEV1,FEV1/FVC,FEF25-75 and PEF were to be (2. 62 ± 0. 97)L,(2. 02 ± 0. 78)L,(0. 77 ± 0. 10),(1. 99 ± 1. 03)L/S and (5. 20 ± 2. 09)L/S for cases as the means of them being (2. 63 ± 0. 90)L,(2. 01 ± 0. 77)L,(0. 76 ± 0. 12),(1. 90 ± 1. 07)L/S and (5. 20 ± 2. 25)L/S for controls,without statistical significance of the difference (all P>0. 05). According to lung function classification of Wheaton AG,et al,type 2 diabetes mellitus did not increase the risks of obstructive lung function decline (OR=0. 94,95%CI:0. 54-1. 66)and restricted lung function decline (OR=1. 09, 95%CI:0. 57-2. 10),and the similar result was observed in COPD (OR=1. 37,95%CI:0. 73~2. 57)after adjusted the risk factors. Conclusion Type 2 diabetes mellitus does not increase the risk of pulmonary function decline and COPD in Southern Chinese.
Keywords：type 2 diabetes mellituslung function declineassociation studyCOPD
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 2840-2843 )