The correlation of glycosylated hemoglobin and blood pressure variability in elderly patients with hypertension and type 2 diabetes mellitus
HUANG Jiang-ming
XU Lin
QIU Jian
MA Jun
Abstract：Objective To investigate the correlation between glycosylated hemoglobin ( HbA1C ) and blood pres-sure variability (BPV) in elderly patients hypertension and type 2 diabetes mellitus (T2DM).Methods A total of 144 elderly patients with hypertension and T 2DM were included.HbA1C and BPV were measured and the correlation between them were analyzed.According to HbA1C level, all participants were divided into normal group (HbA1C <6.0%, n=97), high-normal group (6.0%≤HbA1C <7.0%, n=31) and risen group (HbA1C >7.0%, n=16).The BPV inde-xes correlated to the HbA 1C were analyzed and further compared among the three groups .Results In elderly patients with hypertension and T2DM, HbA1C level was significantly correlated with BPV indexes , including night mean SBP , CV of day SBP, ARV of day SBP, 24-hour SV of SBP and day SV of SBP .The night mean SBP, ARV of day SBP, 24-hour SV of SBP and day SV of SBP in risen group were significantly higher than those in normal group .Meanwhile , day ARV of SBP and day SV of SBP in risen group were significantly higher than those in normal -high group .Conclusion In elderly patients with hypertension and T 2DM, there is a significant correlation between HbA 1C and BPV, positive control of blood glucose level would benefit the BPV control , thereby reducing the target organ damage .
Keywords：elderly hypertensiontype 2 diabetes mellitusglycosylated hemoglobinblood pressure variability
Publication Date：2016-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 3673-3677 )