The effect of dyclonine lubrication on the intubation and extubation stress response and pain tonsillectomy under general anesthesia with intubation
ZHENG Xia
SHE Ying-jun
SONG Xing-rong
Abstract：Objective To study the effect of Dyclonine Lubrication on the intubation and extubation stress re-sponse and pain tonsillectomy under general anesthesia with intubation .Methods Children received tonsillectomy under general anesthesia with tracheal intubation were enrolled and randomly divided into 2 groups ( n=100):Dyclonine group and control group .Dyclonine hydrocholride mucllage ( 1%) was applied as lubricant in dyclonine group , as saline was used in control group as replacement .The hemodynamics record during intubation and extubation , the occurrence of cough, restlessness, edema and spasm of the larynx , as well as the FLACC score 30 minutes after extubation were com-pared.Results HR and MAP in dyclonine group were significantly lower than control group 10 min after tracheal intuba-tion, during intubation , and 5 min and 30 min after tracheal extubation .Moreover , compared with the control group , the occurrence of cough , restlessness, edema and spasm of the larynx were significantly lower in dyclonine group , and so as the FLACC score 30 min after extubation .Conclusion Dyclonine Lubrication can effectively inhibit stress reaction , hoarseness and other respiratory complications during intubation and extubation , with rapid onset and long lasting analgesic effect.
Keywords：dyclonine lubricationtonsillectomyhemodynamicspostoperative pain
Publication Date：2016-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 1775-1777 )