Clinical value of SPECT/CT myocardial perfusion imaging in primary coronary microvascular angina

YUAN Jian-wei; FENG Yan-lin; ZHANG Pei-pei; WANG Yin; LIANG Wei-tang

Abstract：Objective To evaluate the clinical value of myocardial perfusion imaging( MPI) with SPECT/CT in patients with primary microvascular angina. Methods Imaging data of 36 patients with primary microvascular angina ( the experimental group) receiving MPI with SPECT/CT was analyzed retrospectively. Parameters of left ventricular function in the experimental group were compared with a normal control group of 42 cases. Results (1)All of the 36 patients with myocardial ischemia had reversible myocardial ischemia. A total of 70 ischemic segments were detected, wherein multi-segment ischemia accounted for 83. 3%( 30/36 ) . ( 2 ) Of the 70 ischemic segments, 18 ( 25. 7%) were at apex, 22 (31. 4%) in the anterior wall, 19(27. 1%) in the inferior wall, 9(12. 9%) in the septum, 2(2. 9%) in the lateral wall. Among the 70 segments, perfusion defects scores were 1, 2, and 3 in 85. 7%(60/70),11. 4%(8/70) and 2. 9%(2/70), respectively. (3)There was a significant difference between the normal control group and the experimental group in Left ventricular function parameters (LVEF, EDV, SSS and SDS; all P<0. 05). Conclusion The characteristics of MPI with SPECT/CT in primary microvascular angina was mainly reversible myocardial ischemia involving multi -wall segments. The reversible myocardial ischemia can occur in any segment of the myocardial wall, with mild severity. The patients with primary microvascular angina may have concommitant left ventricular function reduction.