Prevalence and influencing factors of hypertension in maintenance hemodialysis patients in Zhengzhou

LU Yuan; HU Xiao-zhou; ZHANG Jin; WANG Shao-ting; LU Yong-shen

Abstract：Objective To investigate the prevalence and influencing factors of hypertension in maintenance hemo -dialysis ( MHD) patients in Zhengzhou .Methods 472 stable cases of uremia patients on MHD for more than three months from 7 blood purification centers in Zhengzhou were chosen .They were divided into three groups according to blood pressure (BP):the normal BP group, the well-controlled BP group and the poorly -controlled BP group.Gender, age, primary disease, dialysis time, body mass index (BMI), types of antihypertensive drugs , body weight gain, serum urea nitrogen (BUN), serum creatinine (Cr), uric acid (UA), parathyroid hormone (PTH), calcium (Ca), phosphorus (P), calcium-phosphorus product (Ca ×P), triglycerides (TG), total cholesterol (TC), hemoglobin (Hb), albumin (Alb) and Kt/V were compared among the three groups .Results (1) 91.5% of 472 MHD patients suffered from hy-pertension.236 (50.0%) cases had poorly -controlled blood pressure, among them 145 (61.4%) patients with high systolic blood pressure , while 6.3%with high diastolic blood pressure .( 2 ) There was no significant difference in age , gender, BMI, BUN, Cr, UA, TG, TC, Ca, P, Ca ×P and Alb among the three groups.(3) Compared with other groups, body weight gain and PTH were higher in the poorly -controlled BP group, and Kt/V was lower (P<0.05). Body weight gain was higher and Kt/V was lower in the well -controlled BP group than the normal BP group (P<0.05). Conclusions Hypertension is common in MHD patients , the majority of whom present as high systolic pressure .Exces-sive weight gain during the interdialysis period , inadequate hemodialysis ( low Kt/V) as well as high PTH are risk factors to poor blood pressure control in MHD patients .