Effect of combination of phytosterols and statins on lipid profile in patients with hypercholesterolemia
HAN Jia-ning
DENG Yu-hong
XIONG Long-gen
LI Guo-qiang
Abstract：Objective To investigate the efficacy of dietary intervention with phytosterols for hypercholesterol-emia,providing new tools for the treatment of hyperlipidemia.Methods Patients with hyperlipidemia who did not meet the treatment goal after two months of out-patient statin therapy were randomly selected.Patients were given different do-ses of phytosterols.Changes in total cholesterol,triglycerides,high density lipoprotein-cholesterol (HDL-cholesterol) and low density lipoprotein-cholesterol (LDL-cholesterol) before the intervention,1 and 3 months after were observed.Results Serum total cholesterol and LDL-cholesterol levels were significantly reduced in the intermediate dose group after three months of dietary intervention and in the high-dose group after a month of dietary intervention.Conclusion Phytos-terols dietary intervention helps improve the patient′s lipid profile whose treatment goals were not met after statin therapy.
Keywords：phytosterolshyperlipidemiastatin therapylipid profile
Publication Date：2015-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 2731-2733 )