Clinical analysis of pediatric central nervous system tumors: a retrospective study of 219 cases
WANG Jian
ZHAO Yi -ying
YANG Qun-ying
SAI Ke
KE Chao
ZHANG Xiang-heng
CHEN Yin-sheng
CHEN Zheng-he
LIN Fu-hua
GUO Cheng-cheng
ZHANG Ji
MU Yong-gao
CHEN Zhong-ping
Abstract：Objective To analyze the pathological diagnosis,treatment strategies and clinical results of central nervous system (CNS) tumors in surgically treated children,and to provide data in setting treatment standard and impro-ving prognosis.Methods Clinical materials were retrospectively analyzed for the surgically treated pediatric patients with CNS tumors.Results There were 219 cases that received surgical treatment.Among these tumors the most common type was of neuroepithelial origin,including pilocytic astrocytomas in 25 cases,astrocytomas (WHO Grade Ⅱ) in 21cases.The common tumor type in adults,meningioma was fewer in our series,while common tumor types in children found in our series were medulloblastomas (18 cases,8.2%),germ cell tumors (24 cases,11.0%) and craniopharyngioma (17 ca-ses,7.8%) .The main clinical manifestations of craniopharyngioma were headache,vomiting,limb paralysis,gait insta-bility,convulsion,and impaired vision.After surgery,31 cases (14%) received radiotherapy only,16 cases (7%) re-ceived chemotherapy only,while 39 cases (17.8%) received radiochemotherapy.Conclusion Pilocytic astrocytoma,germ cell tumor,astrocytoma,medulloblastoma,craniopharyngioma are common types of CNS tumors in children.Surgery is the main treatment,radiotherapy and chemotherapy may improve prognosis for malignant tumor cases.
Keywords：brain tumorcomprehensive treatmentchildrensurgical treatment
Publication Date：2015-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 2621-2624 )