Alterations of target volume and position during radiotherapy for cervical cancer
LEI Huai-yu
ZHANG Shu-xu
ZHANG Guo-qian
PENG Ying-ying
WANG Rui-hao
JIANG Shao-hui
ZHOU Xiang
Abstract：Objective To investigate changes in target volume and position during radiotherapy for cervical canc-er.Methods 20 patients with cervical cancer scheduled for radiotherapy were enrolled.GTV, bladder and rectum vol-ume were compared before and in the mid-phase of radiotherapy, as well as the boundary alterations in the left, right, ventral, dorsal, cranial and caudal directions.Results GTV volumes of all the 20 patients were statistically significantly reduced compared with that before radiotherapy (P<0.05).While the differences in bladder and rectal volume were not statistically significant (P>0.05).GTV, bladder and rectum volumes in the mid-phase of radiotherapy were not less than 70%of that before radiotherapy, with repeat spatial volume ratio not more than 50%.Maximum displacement was in left, right and cranial directions for GTV, in cranial, caudal and ventral directions for bladder, and in cranial, caudal and dorsal directions for rectum.Displacements of the target and the two organs in all 6 directions were statistically significant (P<0.05).Conclusion For patients with cervical cancer, volumes of bladder and rectum change in a random pattern during radiotherapy regimen, along with target and normal tissue movement.As a result, a secondary plan during radio-therapy regimen or adaptive radiotherapy is necessary.
Keywords：cervical cancerradiotherapyvolumedisplacementrepeat spatial volume
Publication Date：2015-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 2463-2465,2466 )