Associations among HbA1C, carotid plaques and cardiovascular events in peritoneal dialysis patients with diabetes mellitus
JIANG Li-ping
LIANG Jian-bo
WANG Ze-bin
ZHAN Jun-lin
Abstract：Objective To investigate the correlations among HbA 1C , carotid plaques and cardiovascular events in peritoneal dialysis patients with diabetes mellitus .Methods Sixty peritoneal dialysis patients , whose original diseases were diabetes mellitus, were divided into two groups according to the serum HbA 1C level.HbA1C and other serum related parameters were assessed , and carotid intima-media thickness ( cIMT) was checked by B-mode ultrasonography .After one year follow-up, the associations among the serum HbA 1C level, deterioration of cIMT and newly -occurring cardio-vascular events were analyzed .Results Significantly higher cIMT and cardiovascular event rate were observed in high HbA1C group than low HbA1C group (P<0.05).After one year follow-up, progression of cIMT and newly occurring car-diovascular events were significantly higher in high HbA 1C group than low HbA1C group.Logistic regression analysis indica-ted that serum HbA1C level was risk factor of cIMT (OR=1.72, 95%CI:0.92~3.87, P=0.024);while serum HbA1C (OR=1.43, 95%CI:0.73~3.46, P=0.012) level and cIMT (OR=3.17, 95%CI:1.38~5.99, P=0.018) were risk factors of cardiovascular events in peritoneal dialysis patients with diabetes mellitus .Conclusion Serum HbA1C is a risk factor of carotid plaques , and serum HbA1C and cIMT were risk factors of cardiovascular events in peritoneal dialysis with diabetes mellitus .
Keywords：diabetes mellitusperitoneal dialysisHbA1Cvascular calcification
Publication Date：2014-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 1345-1347 )