Changes of autonomic nerve system in senile patients with lower epidural anesthesia
Abstract：Objective To study the changes of autonomic nerve in patients with lower epidural anesthesia.Methods 20 patients(ASA Ⅰ～Ⅱ) being anesthesized with lower epidural nerve block were divided into 2 groups; the senile group (n=10) and the young group (n=10). Changes of heart rate (HR), mean arterial blood pressure (MAP) and heart rate variability (HRV) were observed and analyzed 1 d before operation, 15 min following epidural block, 30 min following incision, 2 h, 1 d, 3 d and 7 d after surgery. Results RMSSD(root of mean square R-R interval difference), TP(total power), LF(low frequency), LFnorm(low frequency normal) of HRV, HR and MAP all decreased significantly in the aged. TP and LF in the young group decreased significantly after epidural block, 2 h, 1d after surgery and then returned to the normal value 3 d after surgery, but perioperative HR and MAP did not chang significantly. TP and LF of all time point after lower epidural block in the senile group were significantly lower than that in the young group (P＜0.01). HF(high frequency) and HFnorm(high frequency normal) in the senile group decreased significantly except for the time points after epidural block and before incision, while HF and HFnorm in the young group decreased significantly only at 30 min following incision.Conclusion It is a good way to evaluate the changes of autonomic nerve system with HRV perioperatively. Both anesthesia and surgical trauma could be associated with the disturbances of perioperative autonomic nerve system of the patients, especially in the senile patients. Changes of autonomic nerve system may be one of the important risk factors of cardiovascular events during the perioperative period, especially in the senile patients.
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Publication Date：2001-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 491-493 )