Immunohistochemical study on dendritic cells in epithelial ovarian cancer
Abstract：Objective To study the infiltration of dendritic cells(DC) in epithelial ovarian cancer. Methods Quantitative assessment of interstitial dendritic cells was performed by S-P immunohistochemical method in specimens of maligmant epithelial ovarian tumor (n=48),benign epithelial ovarian tumor(n=30),and normal ovarian tissue(n=30). Results The number of DC in maligmant epithelial ovarian tumor increased significantly as compared with benign epithelial tumor and normal ovarian tissue(P＜0.01).The DC number in maligmant epithelial ovarian tumor was not correlated with histologic types and differentiation grades, but was correlated with lymphocyte infiltration and survival rate. Conclusion DC may play a role in the host immune reaction against tumor and the number of DC in situ can serve as a useful indicator in assessing prognosis.
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Publication Date：2001-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 129-130 )