Measurement and significance of serum CA125, CA199 and CEA in patients with ovarian tumors
Abstract：Objective To study the clinical values of serum CA125,CA199 and CEA in diagnosing ovarian tumor and in evaluating therapeutic effects. Methods MEIA and RIA was used to measure serum CA125,CA199 and CEA in 126 patients with ovarian tumor (benignant: 62 cases, malignant:44 cases and borderline tumor:20 cases) before operation and in 18 patients with borderline or malignant tumor 3-4 weeks after operation. Results ①CA125,CA199 and CEA were significantly higher in patients with borderline and malignant ovarian tumor than in those with benignant tumor. ②There was no significant difference between borderline and malignant tumor in CA125 and CA199 levels except CEA which was higher in patients with malignancy. ③Positive rates of all tumor markers in stageⅠandⅡpatients were lower than those in stage Ⅲ and Ⅳ patients.Combined measurement of CA125 and CA199 could increased diagnostic rates in stageⅠandⅡpatients.④CA125 and CA199 were an important indices index in evaluating therapeutic effects of ovarian cancer. Conclusion CA125 and CA199 have greater values in differentiation diagnosis,clinical staging and evaluation of therapeutic effect in patients with ovarian tumors.
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Publication Date：2001-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 28-30 )