Relationship between ureaplasma urealyticum (UU) or chlamydia trachomatis (CT) infections and spontaneous abortion

doi:10.3969/j.issn.1001-9448.2000.12.010

Abstract：Objective To study the relationship UU and CT infection in spontaneous abortion and the relationship between of UU and CT infection in female genital tract and embryos in utero. Methods Sixty early pregnant women were divided into study group (spontaneous abortion n = 30) and control group (induced abortion n=30). Samples were taken from cervical canal and villus tissue. The polymerase chain reation technique was used to detect UU - DNA and CT - DNA.Eight villus specimens were examined under light and electron microscope. Results The positive rate UU and CT infections in genital tract was 10.0% and 33.3% respectively in the study group and was while 20.0% and 43.3% in control group respectively. There were not significant differences between the two groups (P>0.05). The positive rate of villus UU and CT infections was 16.7% and 26.7% in study group and was 33.3% and 30.0% in control group respectively. There were not significant differences. 37.9% of genital tract UU and CT positive women and 48.4% of negative women were detected to have the same pathogen in villus, but there were not significant differences in two groups. Histological examination did not found specific change among the villus specimens infected by UU and CT. Conclusion Female genital tract and pregnant tissue infected by UU and CT dose not increase early pregnant lose. Detection of UU and CT in cervical canal is not the decisive factor causing embryo infection in utero.