Influences of Yangwei San on prostaglandin and somatostatin in gastrointestinal mucosa of rats
Abstract：Objective To explore the mechanism of Yangwie San(YS) therapy by molecular biology. Methods The levels of prostaglandin (PG) and somatostalin(SS) in gastrointestinal mucosa of SD rats were investigated after ten- day gastric infusion of YS in a model of gastric mucosa damage induced by indomethacin. Results YS can markedly increased the levels of PG(249.42 pg/ml) and SS (2.020 pg/ml) in damaged gastrointestinal mucosa induced by indomethacin, significantly higher than those of the control group( P < 0.01). Condusion YS can increase the secretion of PG and SS in gastrointestinal mucosa, one of mechanism to stregthen gastric mucosa protective barrier.
Keywords：Yangwei San Prostaglandin Somatostatin Rats
Publication Date：2000-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：2( 1008-1009 )