Cross-species Transmission Mechanisms of Streptococcus suis Influenced by Climate and Geographical Factors
WU Hanguang
LI Yingxin
CHEN Yuqing
SHI Yuanguo
LI Fan
LI Wenxuan
ZHOU Jianzhuo
KE Yankun
Abstract：Streptococcus suis,S.suis is a significant zoonotic pathogen exhibiting distinct spatiotemporal distribution patterns in cross-species transmission.This review systematically examines how climate and geographical factors influence the transmission dynamics of S.suis.Through comprehensive analysis of global literature from 2000 to 2024,we demonstrate that:climate elements regulate both the seasonality and intensity of transmission risk by affecting pathogen survival in the environment,host immune status,and vector activity;geographical isolation shapes the genetic diversity and population structure of S.suis in different regions,forming genotype distribution patterns with distinct regional characteristics;Southeast Asia is a global transmission"hotspot",where the combination of high temperature and humidity climate with foodborne transmission significantly increases human infection risk;serotype 2 S.suis shows obvious advantages in cross-species transmission with strong"serotype filtering"effects.Based on the climate-geography-pathogen ternary interaction mechanism,multi-factor risk assessment models and differentiated prevention strategies are proposed to provide theoretical basis for constructing scientific early warning systems and formulating precise control measures.
Keywords：Streptococcus suisZoonotic diseaseCross-species transmissionClimatic factorsGeographical distribution
Publication Date：2025-12-18
Online Publishing Date：2025-12-31(First online date of this platform, not the publication date of the document)
Pages：6( 35-40 )