Echocardiographic assessment of right ventricular function in obese patients with comorbid hypertension
ZHAO Jingjing
ZHU Tingting
XUE Jiping
Abstract：Objective To evaluate right ventricular(RV)function in obese patients with hypertension via two-dimensional speckle tracking and three-dimensional echocardiography.Methods This study enrolled 125 obese patients from Shanxi Bethune Hospital from October 2023 to October 2024,dividing them into two groups:63 patients with pure obesity and 62 patients with obese and hypertension.The control group comprised 58 healthy volunteers during the same period.All subjects underwent conventional echocardiography,and right ventricular septal longitudinal strain(RVSLS)and right ventricular free wall longitudinal strain(RVFWLS)were obtained by using two-dimensional speckle tracking imaging(2D-STI).Right ventricular end-diastolic volume(RVEDV),end-systolic volume(RVESV),stroke volume(RVSV),ejection fraction(RVEF),tricuspid annular plane systolic excursion(TAPSE)and fractional area change(FAC)were obtained by using real-time three-dimensional echocardiography.Baseline data,routine echocardiography parameters,right ventricular strain parameters,three-dimensional volume,and function parameters were observed and compared among the groups.Results Compared with controls,the obesity-alone group exhibited increased RVEDV,RVESV,and RVSV,along with reduced TAPSE and FAC.The obesity-with-hypertension group demonstrated significantly higher RVEDV and RVESV than the obesity-alone group(P<0.05).RVSLS and RVFWLS were impaired in both obese subgroups compared to controls obesity-alone.Furthermore,the obesity-with-hypertension group had lower RVSLS and RVFWLS than the obesity-alone group(P<0.05).Multivariate linear regression analysis showed that the right ventricular free wall longitudinal strain was independently associated with the systolic blood pressure,LVMI,and BMI(P<0.05).Conclusion Obesity impairs right ventricular function,with hypertension exacerbating this impairment.
Keywords：obesityhypertensionright ventricletwo-dimensional speckle-tracking imagingthree-dimensional echocardiography
Publication Date：2026-01-20
Online Publishing Date：2026-02-04(First online date of this platform, not the publication date of the document)
Pages：6( 108-113 )