Analysis of risk factors and construction of prediction model for communicating hydrocephalus secondary to posterior fossa tumors in children

ZHOU Difan; SONG Ye

doi:10.12122/j.issn.1674-4500.2025.12.16

Abstract：Objective To analyze the influencing factors and independent risk factors of postoperative communicating hydrocephalus in children with posterior cranial fossa tumors,and construct a predictive model to provide a basis for preoperative risk assessment and postoperative management.Methods A retrospective analysis was conducted on the clinical data and imaging information of 113 children with posterior cranial fossa tumors in the Department of Neurosurgery of Women and Children's Medical Center,Affiliated to Guangzhou Medical University from December 2021 to December 2024.Cross-tabulation analysis and chi-square test were performed on all categorical variables and whether secondary communicating hydrocephalus occurred to evaluate the correlation between each categorical variable factor and the outcome.Binary Logistic regression analysis was used to predict independent risk factors.Results The body weight of the children,GCS score at admission,preoperative obstruction,tumor location,intraoperative blood loss,operation time,tumor pathology,postoperative infection,and peak red blood cells in cerebrospinal fluid were significantly correlated with the occurrence of secondary communicating hydrocephalus after surgery(P<0.05).Among them,postoperative intracranial infection was an independent risk factor for secondary communicating hydrocephalus after posterior cranial fossa tumor surgery.Conclusion Postoperative intracranial infection is an independent risk factor for secondary hydrocephalus,so the risk of infection should be reduced as much as possible,and targeted treatment should be provided in a timely manner.