Ciprofol in geriatric patients:current evidence and clinical advancements
LI Boning
CHEN Jialin
TANG Jianjun
Abstract：With the extension of life expectancy,population aging and the increasing healthcare demands of elderly patients have become pressing realities.Aged patients often experience diminished physiological reserve and progressive deterioration across multiple systems including physiological,metabolic,and sensory functions resulting in reduced tolerance to intravenous anesthetics.Ciprofol is a novel non-barbiturate intravenous anesthetic independently developed and recently approved in China.Existing evidence indicates that ciprofol exhibits characteristics such as rapid onset,faster recovery,reduced injection pain,higher potency,and a wider safety window.However,most studies to date are small,single-center investigations lacking rigorous evidence grading,particularly in the context of clinical application in elderly patients.Based on current research,this review summarizes the clinical use of ciprofol in the elderly population,with the aim of supporting its rational administration in this demographic and proposing directions for future research.
Keywords：ciprofolanesthesiaclinical applicationgeriatric patients
Publication Date：2025-11-20
Online Publishing Date：2025-12-16(First online date of this platform, not the publication date of the document)
Pages：7( 1450-1456 )