Study on differences in MSCT signs and platelet parameters and combined diagnosis among different pathological types of acute appendicitis
CHANG Cancan
ZHANG Zhenqi
WANG Xia
YANG Qing
Abstract：Objective To explore the diagnostic value of multi-slice spiral CT(MSCT)combined with platelet parameters[platelet count(PLT),mean platelet volume(MPV)]on different pathological types of acute appendicitis(AA).Methods A total of 135 AA patients who were treated in the hospital from January 2022 to December 2024 were retrospectively selected and divided into simple AA group(n=25),suppurative AA group(n=100)and gangrenous AA group(n=10)according to the pathological results.All patients received preoperative MSCT examination,PLT detection and MPV detection after admission.The imaging differences and diagnostic value of MSCT combined with PLT and MPV on different pathological types of AA were analyzed.Results There were no significant differences in MSCT signs such as fecal impaction,cecal end wall thickening and local lymph node enlargement among different pathological types of AA(P>0.05).The appendix diameter and appendix wall thickness in the gangrenous AA group were successively higher than those in the suppurative AA group and the simple AA group(P<0.05).Compared with the suppurative AA group and the simple AA group,the proportion of pneumatosis outside the appendix wall was higher in the gangrenous AA group,and compared with the simple AA group,the proportion of effusion around the appendix was higher in the suppurative AA group and the gangrenous AA group(P<0.05).The PLT in the suppurative AA group and the gangrenous AA group was higher while the MPV was lower compared to the simple AA group(P<0.05).The areas under the curves of MSCT sign fitting model,platelet parameter fitting model and combined fitting model in the diagnosis of different pathological types of AA were 0.860(95%CI 0.766-0.954),0.817(95%CI 0.699-0.935)and 0.920(95%CI 0.848-0.992)respectively.Conclusion AA has typical MSCT signs,such as enlarged appendix diameter and appendix wall thickness,pneumatosis outside the appendix wall,and effusion around the appendix.In addition,MSCT signs combined with PLT and MPV can provide a comprehensive judgment regimen for differentiating different pathological types of AA.
Keywords：acute appendicitismulti-slice spiral CTplatelet parameterspathological types
Publication Date：2025-09-20
Online Publishing Date：2025-10-22(First online date of this platform, not the publication date of the document)
Pages：6( 1174-1179 )