Predictive value of head CT combined with PLR and D-dimer for rehabilitation effects of Brunnstrom stage-based functional training in stroke patients during convalescence
LI Hongxia
LIN Weiwei
CHEN Meijiao
Abstract：Objective To explore the predictive value of head CT combined with platelet-to-lymphocyte ratio(PLR)and D-dimer(D-D)for rehabilitation effects of Brunnstrom stage-based functional training in stroke patients during convalescence.Methods A total of 126 stroke patients in convalescence who received Brunnstrom stage-based functional training in Zhejiang Rehabilitation Hospital from January 2023 to December 2024 were selected.After one month of treatment,the Fugl-Meyer Assessment(FMA)was used to evaluate rehabilitation effects,and patients were divided into the good effect group and the poor effect group.Head CT findings,PLR,and D-D level before rehabilitation training were compared between the two groups.The ROC curve was used to evaluate the predictive value of head CT combined with PLR and D-D for rehabilitation effects of Brunnstrom stage-based functional training in stroke patients during convalescence.Results Among the 126 stroke patients in convalescence,79(62.70%)showed good rehabilitation effects,with a FMA score of 49.91±1.02.47(37.30%)showed poor rehabilitation effects,with a FMA score of 43.57±1.13.The proportion of abnormal head CT findings,PLR,and D-D level in the poor effect group were higher than those in the good effect group(P<0.05).Multivariate logistic regression analysis revealed that head CT findings,PLR,and D-D were independent factors influencing rehabilitation effects of Brunnstrom stage-based functional training in stroke patients during convalescence(P<0.05).ROC curve analysis showed that the optimal cutoff values of PLR and D-D for predicting rehabilitation effects of Brunnstrom stage-based functional training in stroke patients during convalescence were 150.09 and 208.85 ng/mL,respectively.The AUC and specificity of combination of head CT,PLR and D-D for predicting rehabilitation effects of Brunnstrom stage-based functional training in stroke patients during convalescence were 0.822 and 89.87%,which were higher than those of any single indicator(P<0.05).Conclusion Head CT findings,PLR,and D-D level are independent factors influencing rehabilitation effects of Brunnstrom stage-based functional training in stroke patients during convalescence.In addition,combined use of head CT,PLR and D-D can enhance the prediction of rehabilitation effects of Brunnstrom stage-based functional training in stroke patients during convalescence.
Keywords：head CTplatelet-to-lymphocyte ratioD-dimerstrokefunctional training based on Brunnstrom stagesrehabilitation effectpredictive value
Publication Date：2025-09-20
Online Publishing Date：2025-10-22(First online date of this platform, not the publication date of the document)
Pages：6( 1157-1162 )