Value of cardiac magnetic resonance late gadolinium enhancement in diagnosing dilated cardiomyopathy

WU Huimin; CHENG Ziwang; WANG Hancheng; DU Xunsong

doi:10.12122/j.issn.1674-4500.2025.09.13

Abstract：Objective To investigate the application value of cardiac magnetic resonance imaging with late gadolinium enhancement(CMR-LGE)in the diagnosis of dilated cardiomyopathy(DCM),and to compare the diagnostic results of CMR-LGE with those of echocardiogram(UCG).Methods A retrospective study was conducted on 36 patients diagnosed with DCM upon discharge from Anhui Second Provincial Hospital from January 2023 to March 2025.All patients underwent both CMR-LGE(observation group)and UCG(control group)examinations.Within the observation group,29 patients were CMR-LGE positive for DCM(observation subgroup 1),and 7 were CMR-LGE negative(observation subgroup 2).Within the control group,20 patients were UCG positive for DCM(control subgroup 1),and 16 were UCG negative(control subgroup 2).Differences in diagnostic results,CMR-derived parameters,and clinical specificity parameters were analyzed between the groups.Results CMR-LGE confirmed the diagnosis in 29 cases,which was significantly higher than the 20 cases diagnosed by UCG(P=0.014).In observation subgroup 1(CMR-LGE positive),the left ventricular end-diastolic volume index,left ventricular end-systolic volume index,and myocardial mass index were significantly higher than those in observation subgroup 2(CMR-LGE negative).Conversely,body surface area,left ventricular ejection fraction,and stroke volume index were significantly lower in observation subgroup 1 compared to observation subgroup 2(P<0.05).ROC curve analysis demonstrated that SVI had the highest diagnostic efficacy for DCM,with an AUC of 0.990.Conclusion CMR-LGE demonstrates higher sensitivity in diagnosing DCM compared to UCG.Its quantitative parameters provide valuable reference for clinical diagnosis and treatment.