Comparison of the therapeutic effects of endoscopic variceal ligation and endoscopic cyanoacrylate injection for the treatment of esophageal and gastric variceal bleeding with cirrhosis
PU Wenfeng
ZHANG Yan
HU Luli
HE Qinli
SUN Liang
WEI Fuxia
Abstract：Objective To evaluate and compare the clinical outcomes of endoscopic variceal ligation(EVL)and endoscopic cyanoacrylate injection(ECI)for the treatment of esophagogastric variceal bleeding(EVB)in cirrhotic patients.Methods A total of 124 patients with cirrhotic EVB who were admitted to Nanchong Central Hospital from January 2022 to January 2025 were selected and randomly divided into two groups using a random number table method:the ECI group and the EVL group,with 62 patients in each group.The two groups were evaluated for clinical efficacy,success of hemostasis,clinical indicators,early rebleeding rates,blood biochemistry,and complications.Results There were no statistically significant differences between the EVL and ECI groups in terms of overall efficacy,hemostasis success rate,bleeding cessation time,transfusion volume,hospital stay and early rebleeding rate(P>0.05).The EVL group had lower hospitalization costs compared to the ECI group(P<0.05).Biochemical indicators at 6 weeks post-treatment showed improvement in both groups compared to pre-treatment levels(P<0.05),with no significant differences between the groups(P>0.05).The incidence of postoperative complications in the EVL group was 17.74%,mainly fever and esophageal stenosis,which was lower than the 37.10%in the ECI group,mainly fever and ulcers(P<0.05).Conclusion Both ECI and EVL are effective treatments for cirrhotic EVB.However,compared with ECI,EVL treatment can reduce hospitalization costs and minimize the occurrence of complications.
Keywords：cirrhosisesophagogastric variceal bleedingendoscopic variceal ligationendoscopic cyanoacrylate injection
Publication Date：2025-08-20
Online Publishing Date：2025-09-22(First online date of this platform, not the publication date of the document)
Pages：7( 1003-1009 )