Progress in the prognosis evaluation of patients with acute pulmonary embolism
SONG Jianxia
YANG Yue
CHEN Rong
WANG Min
YU Yaxi
YANG Fei
Abstract：Acute pulmonary embolism(APE)is a serious health-threatening syndrome characterized by an extremely high mortality and disability rate,therefore,early diagnosis,treatment and prognosis assessment of patients with APE are critical.Inflammatory response and coagulation processes are important links in the formation of embolism and are involved in this pathophysiological process.Pulmonary vascular remodeling is often correlated with the extent of pulmonary artery involvement and the degree of right heart dysfunction.Key imaging parameters,including the longest diameter of the right ventricular short axis to the longest diameter of the left ventricle short axis ratio,the Qanadli index,pulmonary artery diameter,and pulmonary artery dilation,are crucial for predicting poor prognosis in APE.This article aims to review recent advancements in clinical features,imaging parameters,serum biomarkers and their combinations for predicting the prognosis of patients with APE.The goal is to enhance the prognostic accuracy of APE,assist clinicians in better risk stratification and personalized treatment planning and ultimately improve patient outcomes.
Keywords：acute pulmonary embolismserum biomarkerslongest diameter of right ventricle short axis to the longest diameter of left ventricle short axis ratioQanadli indexprognosis
Publication Date：2025-07-20
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：6( 905-910 )