Correlation of high-resolution magnetic resonance plaque parameters with short-term prognosis and recurrence in intracranial atherosclerotic stenosis patients
DA Xin
WEI Xiaolian
ZHANG Yuge
LIU Bingjie
YUAN Bin
Abstract：Objective To investigate the clinical value of high-resolution magnetic resonance vessel wall imaging(HRMR-VWI)in the short-term prognosis and recurrence of patients with intracranial atherosclerotic stenosis(ICAS)type cerebral infarction.Methods A total of 175 hospitalized patients who were treated at the First Affiliated Hospital of Xinxiang Medical College from October 2023 to September 2024,met the diagnostic criteria for ICAS type cerebral infarction,and underwent HRMR-VWI were included.Patients were followed up for 90 days.According to their neurological functional recovery and the presence of stroke recurrence,they were divided into good prognosis group(mRS≤2)vs poor prognosis group(mRS>2)and stroke recurrence group vs non-recurrence group.Binary logistic regression,COX regression,and other methods were used to analyze the correlation between plaque parameters and adverse outcomes.Results Univariate analysis results showed that severe vascular stenosis,plaque enhancement,and moderate-to-severe stroke were more common in patients with poor prognosis,and their serum HbA1c levels were higher.In the stroke recurrence group,a history of diabetes,a history of stroke,plaque enhancement,and moderate-to-severe stroke were more common.Multivariate analysis found that severe vascular stenosis(P=0.027,OR=5.041,95%CI:1.199-21.191)and moderate-to-severe stroke(P<0.001,OR=104.048,95%CI:21.773-497.226)were independent risk factors for poor prognosis,while a history of stroke(P=0.023,HR=2.620,95%CI:1.140-6.023)and plaque enhancement(P=0.025,HR=5.381,95%CI:1.230-23.546)were independent risk factors for stroke recurrence.Conclusion Severe vascular stenosis and moderate-to-severe stroke were independent risk factors for 90-day poor prognosis in ICAS patients,while plaque enhancement and a history of stroke were independent risk factors for 90-day stroke recurrence in ICAS type stroke patients.
Keywords：high-resolution magnetic resonanceintracranial atherosclerotic stenosisprognosisstroke recurrence
Publication Date：2025-07-20
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：7( 880-886 )