Advances in quantitative magnetization imaging for the diagnosis of Alzheimer's disease
PAN Xingyong
LIU Ying
YAN Hao
Abstract：As the number of patients with Alzheimer's disease(AD)continues to rise globally,there is an urgent clinical need for early diagnosis and treatment.Currently,traditional methods for confirming AD diagnosis,such as biomarker detection,still face issues such as invasiveness,radiation risks,and high costs.Given the pathological characteristic of iron deposition in the brains of AD patients,quantitative susceptibility mapping(QSM)can be employed for non-invasive and sensitive detection and quantification.This article reviews the application value of QSM in AD diagnosis,including its ability to reflect AD pathology,the distribution of iron deposition in brain regions,and its correlation with biomarkers.Additionally,it explores the advantages,limitations,and potential for assessing treatment efficacy of QSM.
Keywords：Alzheimer's diseasemild cognitive impairmentquantitative susceptibility mappingiron deposition
Publication Date：2025-06-20
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 781-785 )