The value of multimodal ultrasound quantitative parameters in predicting the risk of cervical lymph node metastasis in papillary thyroid carcinoma
MA Rong
SHAO Chunhui
LUO Yongke
LÜ Pin
WEI Gege
Abstract：Objective To investigate the value of multimodal ultrasound characteristics and quantitative measurement parameters in predicting the risk of cervical lymph node metastasis of thyroid papillary carcinoma(PTC).Methods Clinical data of 117 patients with PTC confirmed by surgery and pathology from October 2022 to October 2024 at Baoji People's Hospital were retrospectively analyzed.The quantitative parameters of Emean and ER of SWE,SEmean and SR of SE,and the ascending slope,peak intensity(PKI),rising time(RT),peak time(TTP),mTIC and area under time intensity curve(TIC-AUC)of CEUS were analyzed.The postoperative pathological results were divided into two groups(non-metastatic group and metastatic group)to compare the diagnostic value of each quantitative parameter between the two groups.Univariate and multivariate binary Logistic regression analysis was used to compare the risk factors of cervical lymph node metastasis between the two groups.Results In the cervical lymph node metastasis group,the proportion of male,fuzzy nodule edge,small intracodular calcification and nodular invasion capsule was higher than that in the non-metastatic group,with statistical significance(P<0.05).Among the quantitative parameters of multimodal ultrasound in the two groups,the strain elastic imaging strain ratio SR in the non-metastasis group was significantly different from the quantitative parameters of CEUS PKI and TIC-AUC in the metastasis group(P<0.05).When the optimal threshold value SR≤2.77,PKI≤14.00dB,TIC-AUC≤1668.09 dB·s,the risk of cervical lymph node metastasis was greater.Multivariate binary Logistic regression analysis of the two groups of patients showed that males,intra nodular fine calcification,nodular invasion capsule and CEUS parameters PKI,TIC-AUC were independent risk factors for cervical lymph node metastasis of PTC(P<0.05).Conclusion Male,intratodular fine calcification,nodular invasion capsule and CEUS parameters PKI≤14.00 dB and TIC-AUC≤1668.09 dB·s have certain value in predicting the risk of cervical lymph node metastasis of PTC,and can provide certain reference for clinical decision-making.
Keywords：papillary thyroid carcinomacervical lymph node metastasisshear-wave elastic imagingstrain elastographycontrast-enhanced ultrasoundfine needle aspiration cytologydiagnostic value
Publication Date：2025-04-20
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：7( 502-508 )