SonoLiver contrast quantitative analysis and dynamic vascular model:an effective auxiliary means for the diagnosis of prostate lesions
ZUBAIRE·Yisikandaier
JIA Zhiying
ZHAN Tianlong
ASIYEMU·Abudilimu
ZHANG Tongli
Abstract：Objective To explore the application value of SonoLiver contrast-enhanced quantitative analysis and dynamic vascular model(DVP)in the diagnosis of prostate lesions.Methods A total of 103 patients who visited our hospital and underwent prostate biopsy were selected.According to the pathological results,they were divided into prostate cancer group(n=56),benign prostatic hyperplasia group(n=22),and prostatitis group(n=25).The contrast-enhanced patterns(contrast-enhanced intensity,enhancement pattern,whether the enhancement was uniform,and wash-out time),contrast-enhanced parameters[maximum echo intensity ratio(Imax),time to peak(TTP),rise time(RT),50%point of the rising slope(Rs50),10%-90%point of the rising slope(Rs1090),fall time(FT),50%point of the falling slope(Fs50),fall half time(FHT),mean transit time(mTT),area under the curve during the perfusion phase(WinAUC),perfusion rate(WinR),wash-out rate(WoutR)]and DVP curve waveforms were compared among the groups.Results When comparing the contrast-enhanced patterns between the benign prostatic hyperplasia group and the prostate malignancy group,the differences in contrast-enhanced intensity,enhancement pattern,and wash-out time were statistically significant(P<0.05),while the difference in whether the enhancement was uniform was not statistically significant(P>0.05).When comparing the contrast-enhanced parameters between the prostate cancer group and the prostatitis group,the difference in contrast-enhanced intensity was statistically significant(P<0.05),while the differences in enhancement pattern,whether the enhancement was uniform,and wash-out time were not statistically significant(P>0.05).When comparing the contrast-enhanced parameters between the prostate cancer group and the benign prostatic hyperplasia group,the differences in Imax,TTP,RT,Rs50,Rs1090,FT,Fs50,FHT,mTT,WinAUC,WinR,and WoutR were all statistically significant(P>0.05).When comparing the contrast-enhanced parameters between the prostate cancer group and the prostatitis group,the differences in Imax,TTP,RT,Rs50,Rs1090,Fs50,AUC,WinAUC,WinR,and WoutR were all statistically significant(P<0.05).When comparing the contrast-enhanced parameters between the prostatitis group and the benign prostatic hyperplasia group,the difference in TTP was statistically significant(P<0.05).In the prostate cancer group,the DVP curve waveforms were mainly positive waveforms accounting for 33.93%(19/56)and positive-negative bidirectional waveforms accounting for 57.14%(32/56).In the benign prostatic hyperplasia group,the negative-positive bidirectional waveforms accounted for 50.00%(11/22).In the prostatitis group,the negative waveforms accounted for 32%(8/25)and the negative-positive bidirectional waveforms accounted for 40%(10/25).The differences in DVP curve waveforms between the prostate cancer group and the other two groups were statistically significant(P<0.05).Conclusion SonoLiver contrast-enhanced quantitative analysis and dynamic vascular model have certain reference value in the diagnosis of prostate lesions.
Keywords：prostate tumorcontrast-enhanced ultrasonographydynamic vascular modelquantitative analysis
Publication Date：2025-04-20
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：8( 466-473 )