Research progress of fibroblast activation protein inhibitor PET imaging in the application of myocardial fibrosis
HAN Yanyao
CAI Liang
Abstract：Myocardial fibrosis is a process of cardiac interstitial remodeling,which is a common healing response after cardiac injury.Fibroblast activation protein inhibitor(FAPI)is a novel agent that targets FAP with a high target-to-background ratio.Current research indicates that FAPI plays a key role in the diagnosis of myocardial fibrosis and has become a recent research focus.This article mainly reviews the application of FAPI PET imaging,the forms of myocardial fibrosis,and the current research status of FAPI PET in myocardial fibrosis in various heart diseases,in order to reveal the value of FAPI PET in non-invasive monitoring,early intervention,and improving the prognosis of myocardial fibrosis,which will help its further clinical promotion and application.
Keywords：fibroblast activating protein inhibitorfibroblast activating proteinpositron-emission tomographymyocardial fibrosisreview
Publication Date：2025-02-27
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：6( 247-252 )