Diagnostic value of MRI IDEAL-IQ technique in differentiating aplastic anemia from myelodysplastic syndromes
TIAN Yan
XU Yaping
CUI Yunfu
WANG Dan
CAO Xinshan
Abstract：Objective To evaluate the application value of IDEAL-IQ quantitative assessment of bone marrow fat content and iron content in differentiating between aplastic anemia(AA)and myelodysplastic syndrome(MDS).Methods A total of 44 patients with AA(AA group),25 patients with MDS(MDS group),and 28 healthy volunteers(control group)were included.We quantitatively measured the bone marrow fat content and iron content of the right iliac bone.Consistency among three data assessors was analyzed using the interclass correlation coefficient(ICC).Non-parametric tests were employed to compare differences in bone marrow fat content and R2* values among the AA,MDS,and control groups,P<0.05 considered statistically significant.Results The AA group exhibited a significantly higher bone marrow fat content compared to the MDS group and the control group,with significant differences(P<0.05).No statistically significant differences were found in bone marrow iron content among the AA group,MDS group,and control group(P>0.05).Conclusion The IDEAL-IQ technique of magnetic resonance imaging can provide effective technical support for the preliminary differential diagnosis of aplastic disorder and myelodysplastic syndrome from the imaging perspective according to the changes of bone marrow fat content.By evaluating bone marrow fat content,it can assist the clinical selection of treatment.
Keywords：aplastic anemiamyelodysplastic syndromemagnetic resonance imaging
Publication Date：2025-02-27
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：6( 223-228 )