Clinical diagnostic value of multimodal echocardiography combined with strain and tricuspid annulus displacement parameters for right ventricular function in children with mycoplasma pneumonia
WANG Ziyue
LI Hezhou
WU Juan
WANG Xinxia
ZHANG Junling
YANG Po
QI Fangfang
LIU Zhijiao
Abstract：Objective To explore the value of multimodal echocardiographic assessment of right ventricular function in children with Mycoplasma pneumoniae pneumonia(MPP).Methods Forty-five children in the acute phase of MPP(MPP group)and fifty healthy children in the same period(control group)who attended the Third Affiliated Hospital of Zhengzhou University from January to March 2024 were selected.Two-dimensional speckle tracking(STI)technique was used to ascertain right ventricular strain parameters and TAD parameters,and different ultrasound assessment methods such as conventional 2D echocardiography,spectral Doppler,and tissue Doppler imaging(TDI)were applied for right ventricular function examination.Compare the differences in the right ventricular diameter parameters(RVT,RVL),tricuspid valve spectral Doppler parameters(TVE,TVA,TVE/A),pulmonary valve spectral Doppler parameters(PVAT,PV),tricuspid annular tissue Doppler parameters(s,e,a,IVCT,ET,IVRT,TDI-Tei index),right ventricular longitudinal strain parameters(RV4CSL,RVFWSL)with TAD parameters(T1,T2,Tm%,Tm)between two groups of children.Correlation of strain parameters and TAD parameters with myocardiac enzyme spectrum results in the MPP group using Pearson's correlation analysis,respectively.Results TVE and TVA increased,ET shortened,and TDI-Tei index increased in the MPP group compared with the control group(P<0.05).However,there were no significant differences in TVE/A and tricuspid annulus e/a compared with the control group(P>0.05);The right ventricular longitudinal strain parameters(RV4CSL,RVFWSL)and TAD parameters(T1,T2,Tm%,Tm)were reduced compared with the control group(P<0.05);The strain and TAD parameters in the MPP group were negatively correlated with myocardiac enzyme spectrum results,with better correlations between Tm%and LDH,RV4CSL and LDH,Tm%and CK-MB,Tm%and CK,RV4CSL and CK-MB(r=-0.706,-0.658,-0.664,-0.654,-0.636,P<0.05).Conclusion In children with MPP,the overall function of the right ventricle was impaired,with impaired systolic function and no effect on diastolic function.The measurement of right ventricular strain parameters and TAD parameters by STI technique is helpful for early detection and quantitative evaluation of right ventricular myocardial systolic dysfunction in MPP.The higher the myocardiac enzyme spectrum,the lower the right ventricular strain parameters and TAD parameters,and the more severe the subclinical myocardial damage of right ventricle in MPP children.
Keywords：Mycoplasma pneumoniae pneumoniaright ventricular function2D speckle tracking technologytissue doppler imagingmyocardial straintricuspid annulus displacement
Publication Date：2025-02-27
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：7( 211-217 )