Evaluation value of regional leptomeningeal collateral and arterial transit artifact scores in assessing brain function status of patients:based on 3D TOF MRA and 3D-ASL imaging
HE Yilin
DENG Gengying
HE Nianci
SONG Shiqian
CHEN Wei
ZHANG Hui
Abstract：Objective To explore the relationship between regional leptomeningeal collateral(rLMC)scoring assessed via three-dimensional time of flight magnetic resonance angiography(3D TOF MRA),arterial transit artifact(ATA)scoring obtained from three-dimensional arterial spin labeling(3D-ASL)imaging sequences,and cognitive impairment.Methods A retrospective analysis was conducted on 48 patients who underwent brain imaging,including T1WI,T2WI,T2 FLAIR,3D TOF MRA and 3D-ASL at Xiangya Hospital,Central South University,from January 2018 to October 2023.The rLMC and ATA scores were used to evaluate the status of leptomeningeal collaterals,while the patients'activities of daily living(ADL)scores served as reference indicators for assessing cognitive function.Statistical analyses were performed to evaluate the relationships among the three scores.Results There was a statistically significant difference in ADL scores among different rLMC grading groups(P<0.05).There was a significant difference between the ATA and ADL scores(P<0.05).Spearman's correlation coefficient analysis demonstrated a significant positive correlation between ATA and ADL scores(P<0.05).However,no significant difference was found between rLMC and ATA scores based on variance analysis(P>0.05).Conclusion Both rLMC and ATA scores can serve as important imaging indicators for assessing brain function impairment.A well-developed collateral circulation can have a positive impact on the patient's brain function.In particular,changes in secondary meningeal collateral circulation can be used to predict or evaluate the patient's brain function,with the aim of developing personalized treatment plans in clinical practice.
Keywords：dural collateral circulationbrain functionmagnetic resonance angiographythree-dimensional arterial spin labelingartery reached the false film score
Publication Date：2025-02-27
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：6( 191-196 )