Research progress of cognitive dysfunction in type 1 diabetes mellitus
HUA Wenting
LI Xiaotao
TIAN Limin
Abstract：Type 1 diabetes mellitus(T1DM)-related cognitive dysfunction and potential brain impairment have attracted increasing attention with the rising incidence of T1DM and the extension of patient life expectancy.Several studies have demonstrated an association between T1DM and cognitive dysfunction.In recent years,the widespread application of MRI technology has provided objective imaging evidence for exploring the neuropathophysiological mechanisms of brain impairment in T1DM.This article reviews the manifestations of cognitive dysfunction,the application of MRI technology in brain impairment,and the underlying pathological mechanism in patients with T1DM.By summarizing previous research,it aims to help clinicians gain a deeper understanding of the relationship between T1DM and cognitive dysfunction,and to provide new perspectives for future research,with the hope of early identification and intervention for cognitive dysfunction in patients with T1DM.
Keywords：diabetes mellitus type 1cognitive dysfunctionmagnetic resonance imaging
Publication Date：2025-01-27
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：6( 114-119 )