99m TcO4-ectopic gastric mucosal imaging can be used for the diagnosis of Meckel's diverticulum in children

LI Yonghao; ZHANG Kai; LIU Jiangyan

doi:10.12122/j.issn.1674-4500.2024.11.10

Abstract：Objective To explore the clinical value of 99mTcO4-ectopic gastric mucosa imaging in the diagnosis of Meckel's diverticulum in children.Methods A retrospective analysis was conducted on thirty-nine children with clinical suspicion of Meckel's diverticulum who were admitted to the Second Hospital of Lanzhou University from January 2017 to January 2022 due to symptoms such as hematochezia and intestinal obstruction.Basic information,blood routine,99mTcO4-ectopic gastric mucosa imaging,abdominal ultrasound and surgical pathological results were included.Results Among the thirty-nine children,twenty-five were confirmed to have Meckel's diverticulum through surgery.The diagnostic sensitivity of 99mTcO4-ectopic gastric mucosa imaging was 64.00%,the specificity was 92.31%,the positive predictive value was 94.12%,and the diagnostic accuracy was 71.79%.The hemoglobin and red blood cell in the Meckel's diverticulum group were significantly lower than those in the non-Meckel's diverticulum group(P<0.05).The Meckel's diverticulum group was divided into the true positive group(n=16)and the false negative group(n=9)based on the results of 99mTcO4-ectopic gastric mucosa imaging before surgery.The hemoglobin,red blood cell and white blood cell counts in the true positive group were significantly lower than those in the false negative group;the maximum diameter of the lesion in the true positive group was significantly larger than that in the false negative group;pathologically confirmed that all patients in the true positive group had ectopic gastric mucosa,and 6 patients in the false negative group had ectopic gastric mucosa.There was a statistically significant difference in the presence of ectopic gastric mucosa tissue between the two groups(P<0.05).Conclusion 99mTcO4-ectopic gastric mucosal imaging holds significant diagnostic value for Meckel's diverticulum in children,although its accuracy is influenced by various factors.