CT enterography is beneficial to evaluate disease severity in patients with Crohn's disease
CAO Bo
SHEN Hanjie
Abstract：Objective To explore the characteristics of CT enterography(CTE)and their evaluation value for disease severity in patients with Crohn's disease(CD).Methods A total of 82 patients with CD admitted to the hospital were retrospectively enrolled from January 2020 to April 2024.According to CD activity index(CDAI),they were divided into remission group(n=34,CDAI<150 points)and active group(n=48,CDAI≥150 points).All patients underwent CTE.CTE characteristics were compared between the two groups.The evaluation value of CTE characteristics for disease severity in CD patients was analyzed by ROC curves.Results There were differences in enhancement mode,enlargement of mesenteric lymph nodes,increase of mesenteric fat density,tooth comb sign and cellulitis between the two groups(P<0.05).The thickness of intestinal walls,CT values in arterial and venous phases in remission group were lower than those in active group(P<0.05).The results of ROC curves analysis showed that area under the curve values of intestinal wall thickness,arterial CT value,venous CT value and combined detection(parallel mode)for evaluating disease severity in CD patients were 0.857,0.775,0.808 and 0.920,respectively(P<0.05).Conclusion CTE can fully and clearly display intestinal wall and parenteral manifestations in CD patients.CTE quantitative parameters(thickness of intestinal walls,CT values in arterial and venous phases)are beneficial to evaluate disease severity in CD patients.
Keywords：Crohn's diseaseCT enterographyCrohn's disease activity indexdisease severity
Publication Date：2024-11-28
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：6( 1207-1212 )