Comparison of the diagnostic effectiveness of digital breast tomosynthesis,full-field digital mammography,ultrasound and MRI for dense breast lesions
HU Biying
LI Jiaqiang
LUO Chun
ZHOU Tao
LUO Jiaxin
MO Shuqiong
YU Fan
Abstract：Objective To investigate the diagnostic effectiveness of digital breast tomosynthesis(DBT),full-field digital mammography(FFDM),ultrasound and MRI in the diagnosis of dense breast lesions.Methods A retrospective analysis was conducted by two experienced and inexperienced radiologists on 223 dense breast lesions that underwent both FFDM and DBT examinations,as well as a retrospective analysis on 97 dense breast lesions that underwent both FFDM,DBT,ultrasound,and MRI examinations.The dense breast lesions were diagnosed as benign(BI-RADS grade 4a and below)or malignant(BI-RADS grade 4b and above),based on the images of FFDM,DBT,ultrasound and MRI,respectively.All patients underwent surgery to get a pathological diagnosis.Kappa consistency tests and ROC curve were used to compare the efficacy of high-and low-experience radiologists,as well as FFDM,DBT,FFDM+DBT,ultrasound,and MRI in the diagnosis of dense breast lesions.Results In the comparison between senior and junior radiologists using FFDM and DBT,the senior radiologist use DBT to diagnose dense breast lesions had a high degree of consistency with the pathological results(Kappa=0.712),while the junior radiologist use FFDM diagnosis efficiency was lower than that of the junior radiologist use DBT and the senior radiologist use FFDM and DBT(AUC=0.610,0.808,0.652,0.855).In the comparisons between FFDM,DBT,FFDM+DBT,ultrasound and MRI,the diagnostic results of DBT,FFDM+DBT and MR examinations had high consistency with the pathological gold standard,and the consistency increased(Kappa=0.688,0.707,0.792).In all dense breast lesions,the diagnostic efficacy of FFDM,FFDM+DBT and MRI increased gradually(AUC=0.690,0.815,0.888).Conclusion Both junior and senior radiologists can improve their diagnostic efficiency by using the DBT examination method,and the improvement in diagnostic efficiency for junior radiologists is more significant.Radiologists can significantly improve the diagnostic efficiency of mammography by using the DBT technology,and the diagnostic efficiency is equivalent to that of MR.The pathological consistency of DBT is slightly lower than that of FFDM+DBT,but the diagnostic efficiency is equivalent.
Keywords：digital breast tomosynthesisdense breastdiagnostic efficiency
Publication Date：2024-11-28
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：7( 1200-1206 )