Right ventricular quantitative analysis system combined with myocardial injury markers can guide the prognosis of patients with septic shock
ZHANG Yiyao
NIU Kaixuan
LÜ Hongan
ZHAO Shibing
Abstract：Objective To investigate the prognostic value of right ventricular quantitative analysis system(RVQAS)combined with myocardial injury markers in patients with septic shock.Methods A total of 100 patients with septic shock admitted to the Department of Critical Care Medicine of the First Affiliated Hospital of Bengbu Medical University from May 2018 to May 2023 were selected and divided into survival group(n=76)and death group(n=24)according to the prognosis after 28 days,Quantitative medical parameters of the right ventricle of patients were recorded by RVQAS using bedside ultrasound.At the same time,the serum concentrations of myocardial injury markers on the day of admission were collected,and the above results were included in the statistical analysis.Results Right ventricular end-diastolic volume(RVEDV),Right ventricular end-diastolic volume index(RVEDVI),Right ventricular end-systolic volume(RVESV)and Right ventricular end-systolic volume index(RVESVI)in the death group were higher than those in the survival group(P<0.05).right ventricular ejection fraction(RVEF),right ventricular cardiac output,right ventricular cardiac index,right ventricular stroke volume and right ventricular stroke volume index were lower in the death group than in the survival group(P<0.05).The serum concentrations of creatine kinase(CK),creatine kinase isoenzyme and cardiac troponin I(cTnI)in the death group were higher than those in the survival group(P<0.05).Spearman correlation analysis showed that the death of patients was positively correlated with RVEDV,RVEDVI,RVESV,RVESVI,CK and cTnI,and negatively correlated with RVEF(P<0.05).The ROC curve showed that the area under the curve of RVESVI alone was 0.948,and the area under the curve of RVESVI combined with CK was 0.999 in the diagnosis of septic shock,and the predictive value of RVESVI for death was the highest.Conclusion RVQAS measurement of right ventricular function can provide more reference information for the timely and effective treatment of patients with septic shock.RVESVI combined with CK has the highest predictive value for the death of patients,and should be used in clinical practice earlier to bring greater benefits for the early diagnosis and treatment of patients.
Keywords：right ventricular quantitative analysis systemmyocardial markersseptic shock
Publication Date：2024-11-28
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：8( 1155-1162 )