Research progress of CT imaging markers associated with nonalcoholic fatty liver disease and coronary atherosclerosis
ZHANG Yu
LIU Junshi
XING Yan
Abstract：Non-alcoholic fatty liver disease(NAFLD)has emerged as the most prevalent chronic liver disease worldwide,with an increasing incidence on an annual basis.In recent years,a growing body of evidence indicates that NAFLD and coronary atherosclerosis share a multitude of pathophysiological mechanisms,including insulin resistance and systemic inflammation.NAFLD not only promotes the occurrence and development of coronary atherosclerosis,but also is closely related to atherosclerotic cardiovascular disease and represents an independent risk factor for this disease.This article aims to review the research progress of the correlation between NAFLD and atherosclerotic cardiovascular disease from two different but complementary perspectives,including the pathophysiological mechanism of NAFLD promoting coronary atherosclerosis and the correlation studies on imaging markers of NAFLD and coronary atherosclerosis,in order to enhance the identification of risk factors for early coronary atherosclerosis,and provide insights for future individualized clinical diagnosis,treatment and research of NAFLD and atherosclerotic cardiovascular disease.
Keywords：non-alcoholic fatty liver diseasecoronary atherosclerosiscoronary artery calcificationhigh-risk plaquepericoronary adipose tissue
Publication Date：2024-05-28
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 548-552 )