Vertebral bone density changes after percutaneous vertebroplasty based on CT 3D reconstruction

HU Shengxuan; ZHANG Jingwen; ZHU Zhemin; ZENG Weibo; WANG Shuai; SHI Benchao

doi:10.12122/j.issn.1674-4500.2024.04.15

Abstract：Objective To analyze the changes in bone mineral density(BMD)of vertebral bodies after percutaneous vertebroplasty in patients with osteoporotic vertebral compression fractures using Mimics 3D reconstruction.Methods We conducted a retrospective analysis of 45 patients treated from October 2015 to October 2022 at Zhujiang Hospital of Southern Medical University.Patients were categorized into three groups based on the follow-up period post-surgery:group A(1-3 months,n=16),group B(4-12 months,n=14),group C(over 12 months,n=15).CT data were used for 3D reconstruction of vertebral models in Mimics software,which involved differentiating pedicles,ribs,cortical bone,and bone cement to isolate the cancellous bone of vertebrae.Mean CT values were used to represent BMD before and after surgery(BMD1 and BMD2),and the rate of BMD change was calculated.Results In group A,BMD of the treated vertebra was significantly higher post-surgery(P<0.05),with no significant changes in adjacent vertebrae.In group B,BMD of the treated vertebra increased post-surgery(P<0.05),with a decrease in BMD of adjacent vertebrae(P<0.05).In group C,there was no significant change in BMD of the treated vertebra,and a decrease in BMD of adjacent vertebrae(P<0.05).The rate of BMD change in the treated vertebrae between groups A and B was not statistically significant(P>0.05),but both were significantly higher than in group C(P<0.05);the rate of BMD change in adjacent vertebrae in groups B and C was also not significantly different(P>0.05),but both were lower than in group A(P<0.05).Conclusion BMD of the treated vertebra increased in the short term after percutaneous vertebroplasty,with no significant changes in adjacent vertebrae.Over time,BMD decreased in all evaluated vertebrae.