Value of PET/CT in the evaluation of lymphoma heterogeneity
ZHAN Huaying
LI Weilong
YU Lishuo
LIU Zhixiang
Abstract：Lymphoma,a highly heterogeneous tumor primarily derived from lymphocytes,can be effectively staged,restaged,and assessed for treatment response using 18F-FDG PET/CT.This imaging technique evaluates the heterogeneous FDG uptake in tumor cells and changes in the tumor microenvironment.However,conventional PET parameters alone are insufficient for a comprehensive assessment of tumor heterogeneity.This article provides an overview of the role of PET/CT in diagnosing,staging,treating,and assessing the prognosis of lymphoma.Furthermore,it explores the future development direction of PET/CT,including the investigation of new PET parameters,the development of novel agents,and the integration of artificial intelligence.Significant advancements have been made in tumor detection,quantification of heterogeneity,identification,midterm efficacy evaluation,and prognosis prediction.
Keywords：lymphoma18F-FDG PET/CTtumor heterogeneity
Publication Date：2024-04-28
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 220-224 )