Evaluation of left ventricular myocardial work in obese patients with hypertension by left ventricular pressure-strain loop
ZHANG Yanping
ZHANG Jiayu
ZHANG Yanxia
KANG Chunsong
Abstract：Objective To explore the clinical value of left ventricular pressure strain loop in evaluating myocardial work in obese patients with hypertension.Methods Thirty-five patients with simple obesity(obese group),39 patients with obesity combined with hypertension(obese hypertension group)and 38 healthy subjects(control group)were selected from Shanxi Bethune Hospital from May 2020 to August 2022.Conventional echocardiographic parameters,global longitudinal strain(GLS)and myocardial work parameters were measured.The myocardial work parameters included global constructive work(GCW),global work index(GWI),global wasted work(GWW)and global work efficiency(GWE),and the differences of these parameters among the three groups were compared.Results The GLS of the obese group and the obese hypertensive group was lower than that of the control group(P<0.05).Compared with the control group,the GCW,GWI and GWE of the obesity group decreased,and GWW increased(P<0.05).Compared with the obesity group and the control group,the GCW,GWI and GWW of the obesity and hypertension group increased,and GWE decreased(P<0.05).Systolic blood pressure and diastolic blood pressure were positively correlated with GCW,GWI and GWW,and negatively correlated with GLS(P<0.01).BMI was negatively correlated with GCW,GWI and GLS,and positively correlated with GWW(P<0.05).Conclusion Hypertension can aggravate left ventricular dysfunction in obese patients.Left ventricular pressure-strain loop can identify left ventricular myocardial dysfunction in obesity patients with hypertension,which has certain clinical value.
Keywords：obesityhypertensionechocardiographyleft ventricular pressure strain loopmyocardial work
Publication Date：2024-04-28
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：6( 183-188 )