Progress in visualization diagnosis of primary hyperparathyroidism using nuclide imaging
WU Xin'ai
WU Yongjun
WANG Xuemei
Abstract：Primary hyperparathyroidism(PHPT)is a common endocrine disease,often accompanied by calcium and phosphorus metabolism disorders and multi-system lesions.Surgical resection is the main method for the treatment of PHPT.With the popularization and application of minimally invasive surgery,preoperative molecular imaging has become an urgent need for accurate localization.Radionuclide imaging of dual-phase 99mTc-MIBI SPECT/CT,11C-choline and 18F-Fluorocholine PET/CT have always been the focus of preoperative localization research for PHPT.The basic imaging principles of 99mTc-MIBI,11C-choline and 18F-Fluorocholine are presented.The advantages and disadvantages of these radionuclide imaging methods in the clinical applications of PHPT preoperative localization in ectopic/recurrent lesions,polyglandular lesions,inconsistent between PTH elevation with radionuclide imaging findings,and previous neck surgery history were reviewed.
Keywords：primary hyperparathyroidismSPECT/CTPET/CTpreoperative localization
Publication Date：2024-02-28
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 88-92 )