Value of the model constructed by abbreviated MRI combined with ultrasound S-Detect for the differentiation of benign and malignant breast masses

QI Kun; ZHENG Hong; DONG Jinglan; ZHANG Yu; ZHANG Lamei; SUN Jingtao; ZHANG Jinhui

doi:10.12122/j.issn.1674-4500.2023.06.20

Abstract：Objective To investigate the value of abbreviated MRI combined with ultrasound S-Detect model for benign and malignant differentiation of breast masses.Methods A total of 154 patients(159 lesions)who underwent breast ultrasound and MRI from March 2021 to January 2023 at Tangshan Maternal and Child Health Hospital affiliated to North China University of Science and Technology were selected as study subjects.Pathologic biopsy results were used as the gold standard.The abbreviated MRI Ⅰ represented the Breast Imaging Reporting and Data System(BI-RADS)classification model.For abbreviated MRI Ⅱ,BI-RADS classifications of 4A and below were deemed benign,while classifications of 4B and above were deemed malignant.The consistency between the results of different methods for identifying benign and malignant breast masses and pathology results was analyzed with the Kappa test.Logistic regression was used to construct models for identifying benign and malignant breast masses by abbreviated MRI Ⅰ and ultrasound S-Detect+abbreviated MRI Ⅰ.The value of different methods to identify benign and malignant breast masses was evaluated using the ROC curve and decision curve analysis.Results Pathologic findings showed 43 benign and 116 malignant breast masses.The accuracy of ultrasound S-Detect+abbreviated MRI Ⅰ in identifying benign and malignant breast masses was higher than that of ultrasound S-Detect alone(P<0.05).It was also comparable to the accuracy of abbreviated MRI Ⅰ,abbreviated MRI Ⅱ,and ultrasound S-Detect+ abbreviated MRI Ⅱ(P>0.05).The Kappa value of ultrasound S-Detect+abbreviated MRI Ⅰ was higher than that of ultrasound S-Detect,abbreviated MRI Ⅰ,abbreviated MRI Ⅱ,and ultrasound S-Detect+abbreviated MRI Ⅱ.The area under the ROC curve for identifying benign and malignant breast masses with ultrasound S-Detect + abbreviated MRI Ⅰ was higher than that with ultrasound S-Detect,abbreviated MRI Ⅰ,abbreviated MRI Ⅱ and ultrasound S-Detect+abbreviated MRI Ⅱ(P<0.05).Decision curve analysis results showed that within the full risk threshold,the net benefit of identifying breast masses with ultrasound S-Detect+abbreviated MRI Ⅰ was higher than that with ultrasound S-Detect and abbreviated MRI Ⅱ.In the vast majority of the risk threshold range,the net benefit of ultrasound S-Detect+abbreviated MRI Ⅰ in identifying benign and malignant breast masses was higher than that of abbreviated MRI Ⅰ and ultrasound S-Detect + abbreviated MRI Ⅱ.Conclusion The model constructed by abbreviated MRI combined with ultrasound S-Detect can help identify benign and malignant breast masses with a higher value than abbreviated MRI and ultrasound S-Detect alone.