A prognostic model for patients with ischemic cerebral infarction was established based on cerebral MRI perfusion imaging and clinical indicators
LIU Junping
WANG Anqin
GU Haohao
LI Liangyong
Abstract：Objective To investigate the risk factors of poor prognosis in patients with ischemic cerebral infarction,and construct a nomogram model of poor prognosis in patients with ischemic cerebral infarction based on cerebral MRI perfusion imaging and clinical indicators.Methods A total of 100 patients with ischemic cerebral infarction who came to our hospital from July 2021 to January 2023 were selected as the study objects,and cerebral MRI perfusion imaging was performed on the patients.According to the prognosis,patients were divided into poor prognosis group(n=47)and good prognosis group(n=53).Logistic regression analysis was used to screen the risk factors of poor prognosis in patients with ischemic cerebral infarction.R4.2.0 software was used to establish and verify the poor prognosis of patients with ischemic cerebral infarction.Results Logistic regression analysis showed that age≥60 years old,NIHSS score>12 points at admission,major infarction,posterior circulation cerebral infarction,affected time to peak and affected mean transit time were risk factors for poor prognosis in patients with ischemic cerebral infarction,and affected cerebral blood volume and affected cerebral blood flow were protective factors for poor prognosis in patients with ischemic cerebral infarction(P<0.05).The results of the constructed nomogram model for poor prognosis of patients with ischemic cerebral infarction showed that the actual value of the correction curve was in good agreement with the predicted value,the area under ROC curve of the model was 0.778(95%CI:0.735-0.821).When the decision curve showed that the threshold probability was 1%-100%,the net benefit value of the histogram predicting the poor prognosis of patients with ischemic cerebral infarction was higher.Conclusion The nomogram model of poor prognosis of patients with ischemic cerebral infarction based on cerebral MRI perfusion imaging and clinical indicators has high accuracy and clinical application value,and can be used to predict poor prognosis of patients with ischemic cerebral infarction.
Keywords：magnetic resonance imagingperfusion imagingischemic cerebral infarctionprognosiscolumn diagram
Publication Date：2023-12-28
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：6( 1070-1075 )