Multi-mode imaging study and clinical correlation analysis of patients with acute pulmonary thrombus embolism
QI Zhi
HU Enci
LIU Xuemei
Abstract：Objective To explore the correlation between clinical diagnosis and prognosis in patients with acute pulmonary thrombus embolism(PTE)using multi-mode imaging.Methods Fifty-five patients with PTE confirmed in Beijing Hospital of Traditional Chinese Medicine from January 2018 to January 2022 were evaluated retrospectively.Echocardiography,two-dimensional speckle tracking imaging,ultrasound,computer tomography pulmonary angiography(CTPA)and lab marker,including D-dimer,NT-pro brain natriuretic peptide(NT-proBNP)and C-reactive protein results were reviewed.55 patients with PTE were ranked 5 classes according to CTPA results.Associations and correlations between CTPA classes of D-dimer,NT-proBNP,C-reactive protein,velocity of tricuspid regurgitation(VTR),pulmonary systolic pressure(PAPS)and longitudinal strain in right ventricular free wall(RLS)were analysed.Results NT-proBNP,VTR and PAPS showed a gradually increased trend with increased CTPA class and the absolute value of RLS showed a gradually decreased trend with increased CTPA class.The statistical difference among CTPA grading groups was significant(P<0.05).Positive correlations were found between increased NT-proBNP,VTR,PAPS,decreased absolute value of RLS with higher CTPA class(r=0.25,0.24,0.32,0.28,P<0.05).Conclusion Increased NT-proBNP,VTR,PAPS and RLS are significantly associated with the severity of acute PTE patients,which has important clinical value for the diagnosis,treatment and prognosis evaluation of acute PTE patients..
Keywords：pulmonary thrombus embolismacuteNT-proBNPimagingdiagnosis
Publication Date：2023-12-28
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 1065-1069 )